Philip Morris International U.S. White Paper: Misconceptions About Nicotine Among Medical Professionals, FDA Urged to Strengthen Public Education on “Smoke-Free Alternatives”

Aug.19.2025
Philip Morris International U.S. White Paper: Misconceptions About Nicotine Among Medical Professionals, FDA Urged to Strengthen Public Education on “Smoke-Free Alternatives”
Philip Morris International’s U.S. affiliate (PMI America) has released a new white paper stating that U.S. healthcare professionals hold serious misconceptions about smoke-free products, with nearly half incorrectly believing that nicotine causes cancer. As a result, smokers are being denied scientifically accurate harm-reduction advice. The report calls on the U.S. Food and Drug Administration (FDA) to deliver accurate information on smoke-free alternatives to physicians, so they can help adul

Key Points:

  • Barrier to Tobacco Control: PMI’s new white paper reveals that misconceptions among healthcare providers about tobacco harm reduction science hinder smokers from receiving effective guidance.
  •  
  • Proposed Solution: The FDA should take a leadership role in educating healthcare providers about smoke-free alternatives and harm reduction.
  • Supporting Data: About half of healthcare providers mistakenly believe nicotine is carcinogenic, and 93% say the FDA has a responsibility to share information about harm-reduction products.
  • Practical Impact: Misinformation may cause smokers to miss safer alternatives, delaying progress in tobacco control.

 


 

According to PR Newswire (August 18), PMI America’s white paper draws on survey results from healthcare professionals across the United States, highlighting persistent confusion and longstanding misconceptions that prevent providers from offering smokers fully informed advice.

 

PMI America’s Chief Scientific and Regulatory Strategy Officer, Dr. Matthew Holman, stated:

 

“The FDA recognizes that smoke-free alternatives can play an important role in helping adult smokers quit cigarettes, improving both individual and public health. The next step is for the agency to share this information with frontline medical professionals—those most likely to be approached by smokers seeking help.”

 

The white paper was based on survey findings showing that many healthcare professionals are unfamiliar with the science supporting smoke-free products and tobacco harm reduction. This gap is particularly evident with nicotine. As the FDA itself acknowledges, nicotine is not the cause of the most serious health consequences of smoking—including fatal lung disease and cancer. The true culprits are the thousands of chemicals released in tobacco smoke.

 

This is why eliminating tobacco combustion is key to harm reduction. Yet nearly half of healthcare providers—and nearly 60% among those treating many smokers—wrongly believe nicotine is carcinogenic.

 

This information gap has real consequences. If smokers had access to the facts, they might switch to safer alternatives. While complete cessation of tobacco and nicotine remains the best choice, scientific evidence shows that adults who continue using nicotine can significantly reduce their exposure to harm by switching from traditional cigarettes to FDA-authorized smoke-free alternatives.

 

The white paper concludes:

 

“These are critical messages in the fight to end cigarette-related harm. The FDA must communicate them so that healthcare providers, as trusted advisors, can offer fact-based guidance to adult smokers and help them move away from combustible cigarettes.”

 

The report also noted that many providers are unaware of which nicotine products have been reviewed by regulators for safety and efficacy. Some do not even know that combustible cigarettes are the most harmful form of nicotine consumption. For adults aged 21 and over, FDA-authorized smoke-free products are a better choice compared to continued smoking.

 

Survey data further showed that 93% of healthcare professionals believe the FDA has a duty to share information if a specific smoke-free product is shown to lower risks of cancer, cardiovascular disease, or COPD compared to smoking, and 95% said they would pass that information on to their patients.

 

The white paper emphasized that adults of legal age who use nicotine need to be able to consult reliable sources, including their doctors and the FDA, to learn about safer alternatives to cigarettes when they do not plan to quit nicotine entirely.

 

It also called for the FDA to improve its review, authorization, and communication processes regarding safer alternatives available to adults 21 and over, while continuing to prevent youth access to nicotine products. Such measures, the paper argues, would be in the public health interest.

 

Currently, the U.S. lags behind many other countries in launching scientifically validated smoke-free products and encouraging adult smokers to adopt them. As former U.S. Secretary of Health and Human Services and current PMI America advisor Dr. Tom Price noted:

 

“Science should guide our policy. Unfortunately, when it comes to tobacco use—and particularly FDA-authorized smoke-free products—science has not been the driving force in policymaking.”

We welcome news tips, article submissions, interview requests, or comments on this piece.

Please contact us at info@2firsts.com, or reach out to Alan Zhao, CEO of 2Firsts, on LinkedIn


Notice

1.  This article is intended solely for professional research purposes related to industry, technology, and policy. Any references to brands or products are made purely for objective description and do not constitute any form of endorsement, recommendation, or promotion by 2Firsts.

2.  The use of nicotine-containing products — including, but not limited to, cigarettes, e-cigarettes, nicotine pouchand heated tobacco products — carries significant health risks. Users are responsible for complying with all applicable laws and regulations in their respective jurisdictions.

3.  This article is not intended to serve as the basis for any investment decisions or financial advice. 2Firsts assumes no direct or indirect liability for any inaccuracies or errors in the content.

4.  Access to this article is strictly prohibited for individuals below the legal age in their jurisdiction.

 

Copyright

 

This article is either an original work created by 2Firsts or a reproduction from third-party sources with proper attribution. All copyrights and usage rights belong to 2Firsts or the original content provider. Unauthorized reproduction, distribution, or any other form of unauthorized use by any individual or organization is strictly prohibited. Violators will be held legally accountable.

For copyright-related inquiries, please contact: info@2firsts.com

 

AI Assistance Disclaimer

 

This article may have been enhanced using AI tools to improve translation and editorial efficiency. However, due to technical limitations, inaccuracies may occur. Readers are encouraged to refer to the cited sources for the most accurate information.

We welcome any corrections or feedback. Please contact us at: info@2firsts.com

On-Site Report | CTP Details PMTA Backlog, 180-Day Review Goal and sPMTA Process
On-Site Report | CTP Details PMTA Backlog, 180-Day Review Goal and sPMTA Process
FDA’s Center for Tobacco Products detailed new PMTA review data and process changes at the 2026 FDLI conference. Pending PMTAs fell from about 450,000 at the start of 2025 to 135,000 by September 2026. CTP also discussed its 180-day review goal, current sPMTA pilot, alternate-supplier planning, more than 50,300 pending SE reports, and lessons from the nicotine pouch pilot already being applied to ENDS review.
Regulations
Oct.07
U.S. Military Could Test Nicotine Pouches and Vapes for Smoking Cessation as Washington Examiner Cites ZYN and Potential $4 Billion Reduction in Related Defense Costs
U.S. Military Could Test Nicotine Pouches and Vapes for Smoking Cessation as Washington Examiner Cites ZYN and Potential $4 Billion Reduction in Related Defense Costs
The House-passed FY2027 National Defense Authorization Act includes a provision authorizing the defense secretary to conduct a one-year smoking-cessation pilot for active-duty service members. Section 707 lists counseling, nicotine gum and patches alongside what the bill calls "electric nicotine delivery systems," nicotine pouches and heat-not-burn products. A recent Washington Examiner op-ed cited ZYN as an example in arguing for the provision, but the legislation does not name any commercial brand or supplier. ZYN is made by PMI-owned Swedish Match USA, with specified products holding FDA marketing authorizations and modified risk orders.
Sep.20
Indonesia's Influential Islamic Body MUI Urges Vape Permit Freeze, Raising Uncertainty for 200 Manufacturers
Indonesia's Influential Islamic Body MUI Urges Vape Permit Freeze, Raising Uncertainty for 200 Manufacturers
Indonesia's Ulema Council (MUI) published Fatwa No. 131/2026 on November 9, declaring electronic cigarette use, production and trade haram under Islamic religious rules. The council urged the Industry Ministry to prohibit the issuance of vape industry permits and review licensing policies, while calling on the president and parliament to enact a comprehensive ban. On November 10, the Constitutional Court heard a challenge to provisions of the 2023 Health Law seeking a prohibition on vape production, importation, distribution and use. The Health Ministry said on November 11 it was studying stronger restrictions, including a possible ban on circulation, while industry association APVI called for tighter oversight rather than a total ban. Indonesia's Industry Ministry previously estimated the sector comprises about 200 companies, Rp31 trillion ($1.7 billion) in cumulative investment and approximately 100,000 supply-chain jobs. No nationwide statutory ban has been enacted.
Regulations
Nov.12
Ireland Raises Nicotine Product Taxes Again as Cigarettes Gain €1 and Vape Duty Is Set to Jump 40%
Ireland Raises Nicotine Product Taxes Again as Cigarettes Gain €1 and Vape Duty Is Set to Jump 40%
Ireland has increased tobacco excise under Budget 2027 and announced a further rise in its E-liquid Products Tax. From Oct. 7, the tax burden on a pack of 20 cigarettes in the most popular price category increased by €1, with pro-rata increases on other tobacco products. The government plans to raise EPT from €0.50 to €0.70 per millilitre from Jan. 1, 2027, a 40% increase applying to both nicotine-containing and nicotine-free e-liquids. The tobacco duty increase is expected to raise about €63.1 million in a full year.
Regulations
Oct.09
On-Site Report | After FDA Announces Review of PMTA Framework, CTP Director Details Reform Priorities
On-Site Report | After FDA Announces Review of PMTA Framework, CTP Director Details Reform Priorities
FDA CTP Director Bret Koplow used his FDLI keynote in Washington to outline how the agency is rethinking the PMTA framework. He discussed category-specific review, nicotine pouch and sPMTA pilots, AI-assisted review, a 70% reduction in pending applications, and a major staffing constraint: CTP currently has only nine scientific review teams. He also reaffirmed tobacco harm reduction while stressing youth protection, flavored products, risk communication, and the challenge of unauthorized e-cigarettes.
Regulations
Oct.06
Ukraine Raises Excise Stamp Fees for Tobacco, Heated Tobacco and Vape Liquids by 30.5% as Parliament Backs E-Excise Delay to 2027
Ukraine Raises Excise Stamp Fees for Tobacco, Heated Tobacco and Vape Liquids by 30.5% as Parliament Backs E-Excise Delay to 2027
Ukraine's Cabinet of Ministers adopted Resolution No. 1259 on October 15, 2026, increasing excise stamp production fees for tobacco products and e-cigarette liquids by approximately 30.5%, from UAH 0.1643 to UAH 0.2144 per stamp. Fees for alcoholic beverages rose by about 30.2%. Separately, Ukraine's parliament passed Bill No. 15532 on October 13, proposing to postpone the full implementation of electronic excise stamps and traceability for alcohol, tobacco and e-cigarette liquids from November 1, 2026, to July 1, 2027. Parliament cited additional testing, configuration and integration requirements. The bill was sent to the president for signature on October 19.
Regulations
Oct.21