UK Pharmacies Test E-Cigarettes as Smoking Cessation Aid in Pilot Program

Nov.20.2024
UK Pharmacies Test E-Cigarettes as Smoking Cessation Aid in Pilot Program
A pilot program in Kent uses e-cigarettes for smoking cessation, aligning with the government's 2030 smoke-free target, as varenicline returns to NHS prescriptions after safety concerns.

The Community Pharmacy of England (CPE) announced that community pharmacies in Maidstone, Kent, are participating in a pilot program using e-cigarettes as a smoking cessation aid, according to The Pharmaceutical Journal on November 19.

 

Seven pharmacies are offering locally commissioned services, where smoking cessation advisors will provide patients with a voucher for a starter kit and up to a four-week supply of vape liquid. 

 

Patients can also access six other nicotine replacement products, though the service recommends vaping as a short-term aid for quitting smoking.

 

"The pilot is in response to the government's ambition for England to be smoke-free by 2030 and follows reflection by the Medway Public Health Team that, to achieve this, 50% of smokers will need to undertake a quit attempt every year," CPE said.

 

A Cochrane review published in September 2023 found that e-cigarettes, varenicline, and cytisine were the most effective aids for quitting smoking for six months or longer, with similar effectiveness among the three.

 

The review analyzed data from over 150,000 participants and showed that 10–19% of individuals quit smoking with e-cigarettes, 12–16% with varenicline, and 10–18% with cytisine.

 

"Community pharmacies already play a significant role in supporting people to stop smoking, but we believe more value could be created by the sector at a population health level as well as benefits to individuals, in line with the government's desire to achieve a smoke-free country and to reduce the use of vapes," the director of NHS services at the CPE, Alastair Buxton, said.

 

"Stopping smoking is not easy, but research shows that e-cigarettes are nearly twice as effective as nicotine replacement therapies, such as patches and gum, when used in a Stop Smoking Service setting," said Caroline Cerny, deputy chief executive at Action on Smoking and Health.

 

In November 2024, NHS England announced the reintroduction of varenicline for NHS patients, three years after its withdrawal due to high levels of N-nitroso-varenicline, a probable carcinogen. Previously a first-line smoking cessation treatment, varenicline was recalled by Pfizer in October 2021 over these safety concerns.

 

Special Report | Can Nicotine Be Replaced? 6-MN Is Already on the Market While Key Human Evidence Is Still Missing
Special Report | Can Nicotine Be Replaced? 6-MN Is Already on the Market While Key Human Evidence Is Still Missing
Nicotine analogues such as 6-methylnicotine are already appearing in e-cigarettes and oral pouches, even as key human evidence remains limited. A new Nixodine-S study adds nonclinical data showing differences from nicotine in cytotoxicity and receptor activity, while independent studies point to a more complex toxicological picture. With supply-chain activity growing and FDA seeking clearer authority over nicotine analogues, the industry now faces a larger question: what evidence is needed before these substances can credibly replace nicotine?
SCIENCE
Sep.23
Juul Sublicense Reshapes Vuse Alto Patent Bill as Court Ends R.J. Reynolds’ 5.25% Royalty Obligation to Altria
Juul Sublicense Reshapes Vuse Alto Patent Bill as Court Ends R.J. Reynolds’ 5.25% Royalty Obligation to Altria
According to Law360 on August 31, 2026, a federal judge in North Carolina ruled that a patent sublicense between R.J. Reynolds Vapor Co. and Juul Labs Inc. relieves Reynolds of its obligation to continue paying royalties to Altria Client Services LLC over Vuse Alto. A jury had previously found that Vuse Alto infringed three Altria patents and awarded approximately $95.2 million in past damages, after which Reynolds was ordered to pay an ongoing royalty equal to 5.25% of positive net sales. The new ruling finds that a valid sublicense can eliminate future infringement, potentially ending what Altria described as hundreds of millions of dollars in future royalties.
Sep.01
On-Site Report | After FDA Announces Review of PMTA Framework, CTP Director Details Reform Priorities
On-Site Report | After FDA Announces Review of PMTA Framework, CTP Director Details Reform Priorities
FDA CTP Director Bret Koplow used his FDLI keynote in Washington to outline how the agency is rethinking the PMTA framework. He discussed category-specific review, nicotine pouch and sPMTA pilots, AI-assisted review, a 70% reduction in pending applications, and a major staffing constraint: CTP currently has only nine scientific review teams. He also reaffirmed tobacco harm reduction while stressing youth protection, flavored products, risk communication, and the challenge of unauthorized e-cigarettes.
Regulations
Oct.06
Special Report | From New York to Washington: How FDA’s Tobacco Center Is Reworking Product Review
Special Report | From New York to Washington: How FDA’s Tobacco Center Is Reworking Product Review
FDA’s Center for Tobacco Products is reshaping how it approaches tobacco product review. Based on 2Firsts’ on-site reporting in New York and Washington, this report traces CTP’s emerging direction: stronger links between PMTA and tobacco harm reduction, more category-specific review, greater emphasis on decision-relevant science, more predictable timelines and expanded use of sPMTA for product modifications. CTP also acknowledged major constraints, including just nine PMTA review teams, persistent backlogs and limits on hiring capacity.
Regulations
Oct.08
U.S. Expands Illicit Vape Enforcement as ATF Brings PACT Act Powers Into Trade Fraud Task Force
U.S. Expands Illicit Vape Enforcement as ATF Brings PACT Act Powers Into Trade Fraud Task Force
The U.S. Bureau of Alcohol, Tobacco, Firearms and Explosives said on September 23 that it has joined the interagency Trade Fraud Task Force to strengthen enforcement against illegal, misdeclared and smuggled vape and tobacco products. ATF will bring its authority under the Prevent All Cigarette Trafficking Act into the task force, including registration, reporting, shipping and record-inspection requirements covering interstate sales of electronic nicotine delivery systems. ATF said the move will strengthen its ability to trace illicit products from U.S. points of entry through domestic trafficking and distribution networks.
News
Sep.28 by 2Firsts Perspectives
 PMI Opens Generative AI Center in Portugal to Support Global Operations
PMI Opens Generative AI Center in Portugal to Support Global Operations
According to information released by Portugal’s Trade & Investment Agency (AICEP) in July 2026, Philip Morris International (PMI) has established a global Generative Artificial Intelligence Factory (GenAI Factory) at its Portuguese subsidiary Tabaqueira. The center will support PMI’s global operations by developing and deploying AI solutions focused on industrial process optimization, data analytics, operational automation and AI application development. The initiative strengthens Portugal’s role in PMI’s global technology and innovation network.
Aug.27