2Firsts Exclusive PMTA Product: PMTA SUPER MODULE PLAN

May.22

2Firsts launches an exclusive PMTA Super Service Plan featuring the Acceptance Pro Solution and SciAsset Filing Plans.

2Firsts exclusive PMTA product

PMTA SUPER SERVICE PLAN

Acceptance Pro Solution -- 20k $（10 sku）

SciAsset Filing Plans -- 50K $ (10 sku)

Current US Market

· Disposable devices were mostly illicit products that have not been Pre-market authorized by FDA .

· Nicotine pouch related products are booming and growing fast.

· Other type of product such as IOQS Heated Tobacco products are also increasing in the market share.

· Multiple States are requiring products to get PMTA registry in directory before entering each state market.

Acceptance Pro Solution

·The minimum compliance threshold for NPG products entering the US market

· Exclusive Scientific PMTA Acceptance Solution developed by 2Firsts

About 2Firsts Acceptance Pro Solution

2Firsts Acceptance Pro Solutions is a science based enhanced PMTA submission service exclusively launched by 2Firsts. Intended to help new NGP products smoothly to obtain FDA Acceptance Letters - to pass the first compliance threshold for entering the US market.

Intended Client for 2First Acceptance Pro Solution

· Help client to export electronic cigarettes, heated tobacco product and nicotine pouch to the United States in a legal manner

· Brands intending to expand their legal market share in the United States in the next year

· Brand clients intend to register the products in the PMTA directory list of different states

2FIRST Acceptance Pro Service Advantage

·Cost for Acceptance Pro Solution is 20,000$ for 10SKU

·Cost explanation: The PMTA submission service at least 10 sku for each product and costs do not contain testing fee

SciAsset Filing Plans

·Develop products with long-term compliance value and potential for capital premium.

·The scientific pathway exclusively developed by 2Firsts to make new NGP products a "regulatory asset" in the US market.

About SciAsset Filing Plan by 2Firsts

SciAsset Filing is a high-level PMTA robust submission service developed by 2Firsts specifically for new tobacco products (NGPs). Only costs effective PMTA filing plan service provided globally.

SciAsset Filing service will make your product to become an in-depth scientific and compliance value asset in US market, it will also help your product PMTA enter into substantive review phase.

Value of SciAsset Filing Service

Have capability to bring product PMTA application into scientific review phase.

Becoming the positioning foundation of "regulatory assets", it can support financing, brand mergers and acquisitions, and capital valuation, with longer sales periods and lower risk of credit default.

Can expand to FULL PMTA plan, formulate top compliance potential in US market.

Intended company for SciAsset Filing Plan

· Enterprises with long-term strategic layout for the US market

· Let the US compliance product to become the “ top priority “ for the investor and big tobacco hunter in the US market.

·Company that already received PMTA Acceptance letter, hope to get higher level successful achievement in PMTA application.

2FIRSTS PMTA SciAsset Filing Plan Advantage

·Cost for SciAsset Filing Plan is 50,000 $ USD for 10 sku

·Cost explanation: The PMTA submission service at least 10 sku for each product and costs do not contain testing fee

Contact Us

Michelle Zhang

Email：zhangmixuan@2firsts.com

WhatsApp：+79099950122

BAT Malaysia Reports Q3 Results: Net Profit Plummets 89.5%, Stock Price Drops 15%

BAT Malaysia's Q3 results show a sharp 89.5% drop in net profit to RM7 million (approximately $150,000 USD), with revenue also falling to RM300 million (approximately $6.4 million USD). The company attributed the decline to new regulatory requirements, including pictorial health warnings and the retail display ban. Its stock dropped 15.25% to RM4.78 (approximately $1.02 USD).

Oct.31 by 2FIRSTS.ai

Teen Nicotine Use Surges in Pakistan as Flavoured Vapes Spread Rapidly

Pakistan is experiencing a sharp rise in nicotine use among teenagers, driven by widespread availability of flavoured vapes and e-cigarettes. Cheap, sweet-flavoured devices are easily accessible in major cities, and weak enforcement of age limits has enabled young users to adopt vaping at alarming rates. Activists warn that industry marketing falsely portrays e-cigarettes as “safer,” putting youth at risk of long-term addiction and serious health effects.

Nov.14 by 2FIRSTS.ai

Special Report | Belarus to centralize vaping market under state supervision

Belarus is preparing to overhaul its vaping market under tight state control — from monopolizing imports to banning online sales and restricting retail licenses. Officials say nearly 77% of the disposable e-cigarette market is supplied illegally, prompting sweeping regulatory measures that have already sparked strong pushback from consumers and vape retailers.

Dec.03

UK’s Nationwide Crackdown Seizes 111,000 Illegal Vapes in “Machinize 2” Operation

UK police have carried out a nationwide crackdown under Operation Machinize 2, targeting illegal vapes, counterfeit goods, and grey-market businesses. Raids on more than 2,700 premises led to 924 arrests and the seizure of 111,000 illegal vapes, 70kg of cannabis, 4.5m cigarettes, and £10.7m in proceeds.

Nov.11 by 2FIRSTS.ai

Wigan Council and Police Seize Illegal Cigarettes and Vapes Worth £145,000

Wigan Council said its Trading Standards team, working with Greater Manchester Police, has seized large quantities of illegal cigarettes and vaping products across the borough in 2025. The confiscated goods, valued at around £145,000, were linked to multiple enforcement actions, including the temporary closure of retail premises and criminal prosecutions. The council said the measures aim to reduce risks posed by illicit tobacco and vape products, particularly to children.

Dec.25 by 2FIRSTS.ai

China’s Nov. Vape Exports to U.S. Hold at $549 Million, Sustaining High After October’s $591 Million Peak

China’s Nov. vape exports to the U.S. held at $549 million, following October’s $591 million record. 2025 YTD exports reached $3.72 billion, officially eclipsing 2024’s full-year total. This $1.14 billion 60-day surge signals a critical inventory overhang, heightening financial and regulatory risks for manufacturers.

Dec.22