SMOORE Launches Real-Time Monitoring Study on Nicotine Addiction

Jul.07.2022
SMOORE Launches Real-Time Monitoring Study on Nicotine Addiction
The world's largest e-cigarette manufacturer, SMOORE, partners with SIAT to study nicotine addiction and reduce nicotine levels in e-cigarettes.

The world's largest electronic cigarette manufacturer, SMOORE, has announced the launch of the world's first real-time monitoring research project on nicotine addiction.


The vaporization process between e-cigarettes and combustible cigarettes is vastly different, resulting in distinct physical and chemical properties obtained from vaporization and tobacco combustion, respectively.


Electronic cigarette company, SMOORE, has partnered with the Shenzhen Institute of Advanced Technology (SIAT) to undertake a new research project aimed at exploring ways to significantly reduce the nicotine strength in electronic cigarette products and ultimately lower it to non-addictive levels.


Under the direction of Nobel laureate Dr. Erwin Neher, the Neher Laboratory for Neural Plasticity in Shenzhen is the sixth laboratory in Shenzhen named after a Nobel laureate and the first dedicated to neuroscience. The laboratory focuses on researching the human brain and aims to better understand the mechanisms behind diseases and addictions through the use of the latest advanced techniques in modern neuroscience.


This joint study will investigate the secretion and metabolism of dopamine in the brains of animals, and use the data gathered to simulate the human brain state when nicotine is consumed. The laboratory will conduct controlled experiments by exposing test subjects to aerosol environments created by FEELM vaporization and combustion of tobacco.


The project aims to reduce the nicotine intake and subsequent dependence in adult e-cigarette users. This study will also assist SMOORE's research and development team in enhancing the design of e-cigarette devices by improving efficiency through modifying heating elements and atomizers to enhance the vaping experience.


Researchers involved in the project will monitor the aerosolization of e-liquid to gain a better understanding of nicotine absorption, distribution, metabolism in the human body. Additionally, the study will investigate how nicotine is absorbed by different organs to reveal the sensory satisfaction of e-cigarettes.


Dr. Xiong Yuming, Vice President of SMOORE Shenzhen Institute of Basic Research, stated that...


The process of vaporization between electronic cigarettes and combustible cigarettes is vastly different. Therefore, the physical and chemical properties obtained from vaporization and tobacco burning are also completely different. Our study focuses on the potential mechanisms of vaporization and tobacco burning, with the aim of exploring the delivery and absorption of nicotine to reduce the impact of these products on health.


This project is being supported by Southwest University in Chongqing, China. A phased report is expected to be released in the second half of 2022, which will outline the different effects of nicotine on the brain in electronic cigarettes and combustible tobacco products. This joint study on nicotine dependency aims to put an end to global nicotine addiction. Looking towards the future, FEELM aims to provide products that do not lead to nicotine dependency by reducing nicotine levels as close to zero as possible without compromising satisfaction.


This article is a compilation of third-party information, intended for educational and informational purposes only. The copyright for the compiled information belongs to the original media and authors. If there are any copyright infringements, please contact us for removal.



Disclaimer

This article is provided solely for professional research, industry discussion, and informational purposes. Any references to brands, companies, products, technologies, or policies are made for factual reporting and analytical purposes only, and do not constitute endorsement, recommendation, promotion, or advertising by 2Firsts.

Nicotine-containing products, including but not limited to cigarettes, e-cigarettes, heated tobacco products, and nicotine pouches, carry significant health risks. Readers are responsible for complying with all applicable laws and regulations in their respective jurisdictions, including age restrictions and access limitations.

The information contained in this article should not be regarded as investment, legal, medical, regulatory, or commercial advice. While 2Firsts strives to ensure the accuracy and reliability of its content, it does not assume liability for any direct or indirect loss arising from errors, omissions, inaccuracies, or reliance on the information contained herein.

This article is not intended for individuals below the legal age for accessing tobacco or nicotine-related information in their jurisdiction.

 

Copyright Notice

This article is either original content produced by 2Firsts or content reproduced, translated, summarized, or adapted from third-party sources with attribution where applicable. The intellectual property rights of the original content remain with 2Firsts or the respective original rights holders.

No individual or organization may copy, reproduce, distribute, republish, modify, translate, or otherwise use this content without prior authorization. Any unauthorized use may result in legal action.

For copyright-related inquiries, corrections, or removal requests, please contact: info@2firsts.com.

 

AI-Assisted Translation and Editing Notice

Portions of this article may have been translated, edited, or reviewed with the assistance of artificial intelligence tools to improve efficiency and readability. Due to the limitations of AI-assisted translation and editing, discrepancies, omissions, or inaccuracies may exist when compared with the original source.

Where applicable, readers are advised to refer to the original source for the most complete and accurate information. If you identify any errors or believe that any content infringes upon your rights, please contact us at info@2firsts.com, and we will review and address the matter promptly.

Product | PMI Launches ZYN Melts in UK, Extending ZYN Beyond Nicotine Pouches Into Dissolvable Tablets
Product | PMI Launches ZYN Melts in UK, Extending ZYN Beyond Nicotine Pouches Into Dissolvable Tablets
Philip Morris International (PMI) has launched ZYN Melts in the UK, introducing a fully dissolvable oral nicotine tablet format alongside the brand's existing nicotine pouches. The range includes Cool Mint and Peppermint, each offered at 1mg and 2mg of nicotine per tablet, creating four SKUs. Each can contains 20 tablets and is priced at £6.50 in the UK. Unlike ZYN nicotine pouches, Melts are placed between the upper lip and gum and dissolve completely during use.
News
Sep.29 by 2Firsts Perspectives
HG Innovation, linked to IMiracle and ELFBAR, wins China patent for 6-methylnicotine salts covering vaping and oral products
HG Innovation, linked to IMiracle and ELFBAR, wins China patent for 6-methylnicotine salts covering vaping and oral products
HG Innovation Limited has been granted a Chinese invention patent covering 6-methylnicotine salt formulations and their use in oral and vaping products. The technology forms salts between 6-methylnicotine and alicyclic carboxylic acids, with granted claims extending to oral products, atomization substrates and electronic atomization devices. Applicant-generated tests reported differences in oxidation stability, in-vitro cytotoxicity and aerosol heavy-metal performance compared with selected benzoate or lactate controls. HG Innovation is directly linked to the broader IMiracle and ELFBAR business network.
Sep.04
2Firsts Compliance Solutions Hosts PMTA Briefing on FDA Review Signals After JUUL2 Authorization
2Firsts Compliance Solutions Hosts PMTA Briefing on FDA Review Signals After JUUL2 Authorization
Following recent FDA authorizations for JUUL2 and ZYN ULTRA, 2Firsts Compliance Solutions held an online PMTA briefing on Sept. 4 to examine what the decisions may signal about review efficiency, scientific evidence and U.S. market access. Nearly 30 participants from brands, manufacturers, compliance service providers and investment firms joined the discussion.
2Firsts Events
Sep.06
JTI Research Finds 31% of UK Respondents Offered Illicit Tobacco, While 63% of Ennis Packs Lack Duty Marks
JTI Research Finds 31% of UK Respondents Offered Illicit Tobacco, While 63% of Ennis Packs Lack Duty Marks
Multiple JTI-backed studies in the UK and Ireland indicate that illicit tobacco remains visible across consumer interactions and local markets. In the UK, JTI research found that 31% of respondents said they had been offered illicit tobacco products. In Ireland’s Ennis area, a JTI-commissioned empty pack survey found that 63% of sampled cigarette packs did not carry Irish duty-paid markings. The findings come from industry research rather than official government estimates of illicit tobacco market size, but highlight continued concerns among regulators, legitimate retailers and tobacco companies over illicit trade.
Aug.19
Charlie’s Says 30 PACHA Vape SKUs Tentatively Identified for FDA’s Non-Priority Enforcement Public List
Charlie’s Says 30 PACHA Vape SKUs Tentatively Identified for FDA’s Non-Priority Enforcement Public List
Charlie’s Holdings said the U.S. Food and Drug Administration notified the company on June 23, 2026, that 30 PACHA vape SKUs with submitted PMTAs had been tentatively identified for inclusion on a planned public-facing FDA webpage. Under enforcement guidance issued by FDA in May, the webpage is intended to identify certain unauthorized products for which the agency generally does not intend to prioritize enforcement of premarket authorization requirements. Charlie’s disclosed the development alongside second-quarter revenue of $3.8 million, up 116% year over year.
Aug.25
Nicotine Pouches Gain Ground in U.S. Convenience Stores as Vape Unit Sales Fall 14%
Nicotine Pouches Gain Ground in U.S. Convenience Stores as Vape Unit Sales Fall 14%
According to convenience retail publication CStore Decisions, U.S. convenience store tobacco categories are undergoing a structural shift. Based on Circana OmniMarket Total U.S. Convenience data for the 52 weeks ending June 14, 2026, cigarettes remained the largest category with $50.8 billion in sales, but unit sales declined 5.3%. Electronic smoking devices and vaping products also declined, while modern oral nicotine products continued to grow, with nicotine pouch sales rising 29% in dollars and 17% in units. Retailers said changing consumer preferences are reshaping tobacco product assortments at convenience stores.
Regulations
Aug.07