The Importance of Evidenced-Based Debate on E-Cigarettes

Aug.30.2022
The Importance of Evidenced-Based Debate on E-Cigarettes
eSmoking Institute highlights importance of evidence-based discussions on reducing harm and promoting safer e-cigarettes for smokers.

In public discourse, there is an increasing discussion around reducing the health damages associated with smoking, and further research confirms that approximately 95% of e-cigarettes are less toxic than traditional cigarettes, and may assist with smoking cessation.


Marcin Kozłowski, a member of the management board of the eSmoking Institute, a professional research and development center located in Poznan, emphasized the importance of using modern research techniques for reliable, evidence-based public debates. The institute has been dedicated to expanding its research field and has recently purchased equipment to support advanced technology development, including tools that allow for a wider range of testing of water content in nicotine liquids. The institute has also acquired a modern viscometer for dynamic viscosity testing, which will enable them to broaden the scope of their physical and chemical testing.


The head of eSI spoke about the institute's work, stating that their goal is to develop regulations and standards to help smokers better understand the products available in the market. This will further improve the safety of these products. They are also closely monitoring the research of other leading centers in this field. Most importantly, e-cigarette users can now identify that they are using verified, less harmful products and the institute is pleased that more and more people are gaining knowledge about these products.


Marcin Kozłowski is a member of the management board of the eSmoking Institute/Fot.


What is an electronic cigarette?


This is the idea behind the creation of the product, which does not contain tar substances that are known to cause many smoking-related diseases. It works like an inhaler, providing the body with nicotine through the process of evaporating a liquid (based on glycerin and propylene glycol). Therefore, no tobacco is burned, and the amount of toxic substances released in the aerosol compared to traditional tobacco products such as cigarettes is much lower. Clearly, electronic cigarettes are much less harmful than traditional cigarettes, as our research and independent international studies have shown. M. Kozłowski cited a report from the UK Public Health England, which concluded that 95% of the content in electronic cigarettes is tar-free and therefore less harmful compared to traditional cigarettes.


In this context, we often hear about "harm reduction." What exactly does that mean?


Against the backdrop of policies to reduce the harm caused by smoking, it is worth highlighting the role of electronic cigarettes. Some countries in the world, including New Zealand, the United States, and previously mentioned United Kingdom, have implemented policies suggesting that smokers who are unable to quit should switch to the less harmful alternative of electronic cigarettes, even in the form of prescriptions. Surprisingly, this has yielded impressive results. For instance, research conducted in the United Kingdom shows that as many as 52% of its 3.2 million adult electronic cigarette users have quit smoking. Conversely, Spain reports that nine out of ten electronic cigarette users in their country have either completely quit or significantly reduced their nicotine intake. Therefore we have increasingly strong reasons to believe that policies aimed at reducing harm will produce extremely positive results. However, it should be remembered that the products we use must be thoroughly tested.


What else should we know?


The electronic cigarette market offers a variety of options for users, including open or closed systems that only require the replacement of liquid cartridges, such as the Vuse ePod. In my opinion, it is important that we ensure consumers are unable to alter any aspect of the product, so that it can be thoroughly reviewed for its final formulation and ingredients. If we choose to use open systems, only single-use liquids should be permitted. The concept of the finished product would involve providing a substance that is constrained by the entire testing system with regards to its final formulation.


Statement


This article is compiled from third-party information and is intended for industry communication and learning purposes only.


This article does not represent the views of 2FIRSTS and 2FIRSTS cannot confirm the authenticity or accuracy of the content of this article. The translation of this article is only intended for industry communication and research purposes.


Due to limitations in the level of translation, the compiled article may not fully express the content of the original text. Please refer to the original text for accuracy.


2FIRSTS maintains complete alignment with the Chinese government regarding any domestic, Hong Kong, Macau, Taiwan, or foreign statements or positions.


The copyright of compiled information belongs to the original media and author. If there is any infringement, please contact us for immediate removal.



Disclaimer

This article is provided solely for professional research, industry discussion, and informational purposes. Any references to brands, companies, products, technologies, or policies are made for factual reporting and analytical purposes only, and do not constitute endorsement, recommendation, promotion, or advertising by 2Firsts.

Nicotine-containing products, including but not limited to cigarettes, e-cigarettes, heated tobacco products, and nicotine pouches, carry significant health risks. Readers are responsible for complying with all applicable laws and regulations in their respective jurisdictions, including age restrictions and access limitations.

The information contained in this article should not be regarded as investment, legal, medical, regulatory, or commercial advice. While 2Firsts strives to ensure the accuracy and reliability of its content, it does not assume liability for any direct or indirect loss arising from errors, omissions, inaccuracies, or reliance on the information contained herein.

This article is not intended for individuals below the legal age for accessing tobacco or nicotine-related information in their jurisdiction.

 

Copyright Notice

This article is either original content produced by 2Firsts or content reproduced, translated, summarized, or adapted from third-party sources with attribution where applicable. The intellectual property rights of the original content remain with 2Firsts or the respective original rights holders.

No individual or organization may copy, reproduce, distribute, republish, modify, translate, or otherwise use this content without prior authorization. Any unauthorized use may result in legal action.

For copyright-related inquiries, corrections, or removal requests, please contact: info@2firsts.com.

 

AI-Assisted Translation and Editing Notice

Portions of this article may have been translated, edited, or reviewed with the assistance of artificial intelligence tools to improve efficiency and readability. Due to the limitations of AI-assisted translation and editing, discrepancies, omissions, or inaccuracies may exist when compared with the original source.

Where applicable, readers are advised to refer to the original source for the most complete and accurate information. If you identify any errors or believe that any content infringes upon your rights, please contact us at info@2firsts.com, and we will review and address the matter promptly.

IKE Tech Launches IKE 2.0 Compliance Platform for Nicotine Products
IKE Tech Launches IKE 2.0 Compliance Platform for Nicotine Products
IKE Tech launched IKE 2.0 on September 28, initially targeting nicotine products with a platform that combines user identity verification, product authentication, configurable policy controls and data analytics. Products can be authenticated through direct device integration or NFC smart tags. IKE Tech was formed with participation from Ispire's Aspire North America, Berify and Chemular, with Ispire currently holding a 40% interest. Its age-verification component PMTA was accepted by the FDA in 2025 and remains under review. The company did not disclose customer names, commercial deployment volumes, pricing or revenue tied to IKE 2.0.
News
Sep.29 by 2Firsts Perspectives
South Korea Extends Vape Rules to Unmanned Stores After Bringing Synthetic Nicotine Under Tobacco Law
South Korea Extends Vape Rules to Unmanned Stores After Bringing Synthetic Nicotine Under Tobacco Law
South Korea's Ministry of Gender Equality and Family said on September 14 that it plans to designate unmanned e-cigarette stores as businesses where minors are prohibited from entering or working. Operators would be required to verify customers' ages and display notices restricting access by minors. The proposal is open for public comment through October 6. The move follows an April expansion of South Korea's statutory tobacco definition that brought products made with natural or synthetic nicotine under the Tobacco Business Act. Nicotine-free liquids and products using nicotine analogues such as 6-methylnicotine, however, remain an emerging regulatory issue.
Sep.21
As JUUL2 Wins FDA Authorization, Harm Reduction Journal Highlights the Role of Real-World Evidence in Nicotine Product Regulation
As JUUL2 Wins FDA Authorization, Harm Reduction Journal Highlights the Role of Real-World Evidence in Nicotine Product Regulation
A commentary published in the international open-access, peer-reviewed Harm Reduction Journal argues that randomized controlled trials remain central to evaluating smoking cessation efficacy but cannot alone capture real-world uptake, complete switching, longer-term use and population impact of non-combustible nicotine products such as e-cigarettes, heated tobacco and nicotine pouches. The authors frame impact as “reach × efficacy” and call for real-world evidence to complement RCTs. Three days after publication, the FDA authorized three JUUL2 products and highlighted complete switching among adult smokers in explaining its decision, providing a timely regulatory backdrop to the debate.
Sep.08
Former Roche Neuroscience and Rare Diseases Communications Director Ria Kioupritzi Joins PMI as Scientific Affairs Director
Former Roche Neuroscience and Rare Diseases Communications Director Ria Kioupritzi Joins PMI as Scientific Affairs Director
Eleftheria (Ria) Kioupritzi, a biopharmaceutical professional with more than 15 years of experience, has joined Philip Morris International as Director Scientific Affairs within Corporate Affairs. She previously served at Roche as Senior Scientific Communications Director for Neuroscience and Rare Diseases and worked extensively in spinal muscular atrophy. Her earlier career also covered competitive intelligence, clinical and regulatory monitoring, pipeline development and launch preparation. During her time working in Roche's SMA field, Evrysdi passed through several U.S. FDA milestones, including its initial approval, an expanded indication for younger infants and approval of a tablet formulation. Public records do not show that Kioupritzi herself led the FDA submissions.
Sep.22
Ukraine Raises Excise Stamp Fees for Tobacco, Heated Tobacco and Vape Liquids by 30.5% as Parliament Backs E-Excise Delay to 2027
Ukraine Raises Excise Stamp Fees for Tobacco, Heated Tobacco and Vape Liquids by 30.5% as Parliament Backs E-Excise Delay to 2027
Ukraine's Cabinet of Ministers adopted Resolution No. 1259 on October 15, 2026, increasing excise stamp production fees for tobacco products and e-cigarette liquids by approximately 30.5%, from UAH 0.1643 to UAH 0.2144 per stamp. Fees for alcoholic beverages rose by about 30.2%. Separately, Ukraine's parliament passed Bill No. 15532 on October 13, proposing to postpone the full implementation of electronic excise stamps and traceability for alcohol, tobacco and e-cigarette liquids from November 1, 2026, to July 1, 2027. Parliament cited additional testing, configuration and integration requirements. The bill was sent to the president for signature on October 19.
Regulations
Oct.21
Reynolds Puts Nearly 183,000 U.S. Contracted Outlets Under Age-Verification Rules, Covering 94% of Volume — Can It Shift an Unauthorized Vape Market?
Reynolds Puts Nearly 183,000 U.S. Contracted Outlets Under Age-Verification Rules, Covering 94% of Volume — Can It Shift an Unauthorized Vape Market?
Reynolds American says nearly 183,000 U.S. retail outlets are under contract, with its Retail Marketing Plan Contract covering about 94% of company volume and requiring point-of-sale age verification. The company combines those contracts with We Card, TruAge, NACS-linked infrastructure and POS integration, while enhanced Vuse Pro retail rules add ID scanning, purchase limits and stronger underage-sales accountability. The initial Vuse Pro rollout targets about 50,000 stores. The system is taking shape as unauthorized vapor products remain dominant in parts of the U.S. market: a 2026 study estimated they accounted for 69.4% of tracked brick-and-mortar e-cigarette dollar sales in December 2025.
Special Report
Oct.15