Cochrane Lab Reports on Harm Reduction in Heated Tobacco Products

Jul.30.2022
Cochrane Lab Reports on Harm Reduction in Heated Tobacco Products
New Cochrane lab research suggests that switching from traditional cigarettes to HTPs may lower the risk of certain illnesses.

The latest study on heated tobacco products has been released by the Cochrane laboratory. The report follows standard Cochrane screening and data extraction methods, and the majority of the data from the study suggests that harmful substance exposure associated with cancer, heart disease, and respiratory issues is lower with HTP compared to traditional cigarettes. This means that transitioning to HTP may decrease the risk of developing these diseases. However, the research team notes that due to the short duration of the studies, the data is not conclusive enough to fully determine these results.


Researchers emphasized that while they did not find any studies indicating whether HTP helps smokers quit, two Japanese research reports indicated that cigarette sales declined after the introduction of IQOS into the market.


In fact, during a recent online seminar with Kumamaru Hiroya, the Deputy Director of Kawasaki AOI General Hospital, it was stated that while nicotine replacement therapy (NRT), such as nicotine patches, has not produced the expected results, HTP has. Hiroya confirmed that since the local launch of heated tobacco products, the smoking rate has started to significantly decrease.


In short, after attempting nicotine replacement therapy guidance, it did not achieve significant success. However, since 2014, Japan has officially launched three types of heated tobacco products, which have penetrated 25% of the overall smoking population. So far, these products have successfully reduced Japan's smoking rate by 30% within three to four years," said Hiroya in a recent online seminar.


HTP's Aerosol Particles


In other studies, researchers from Kaunas University of Technology in Lithuania conducted an analysis in 2019 examining the levels of aerosol particles, carbonyls, and nicotine in the indoor air of HTPs (referred to as THS in the study). They compared the indoor concentrations of substances such as formaldehyde, acetaldehyde, benzene, toluene, nicotine, and particulate matter 2.5 in THS to the concentrations of traditional cigarettes and other known air pollutants.


According to data, compared to cigarette smoke and other pollutants, any adverse effects of thirdhand smoke (THS) on indoor air quality are negligible. "The use of THS results in several analytes, including nicotine, acetaldehyde, PM2.5 and PNC, being statistically significantly increased, but the levels obtained are much lower compared to those produced by conventional cigarettes (CC) under the same conditions (approximately 16 times, 8 times and 28 times lower for nicotine, acetaldehyde, PNC and PM2.5, respectively).


According to authors Violeta Kauneliene, Marija Meisutovic-Akhtarieva, and Dainius Martuzevicius, "In a controlled environment, the concentration of formaldehyde, toluene, and PM2.5 in THS (and vape) is much lower than in most other sources of pollution, such as traditional cigarettes and hookah.


Click to view the original research report.


Sorry, I cannot complete this task as there is no original text to translate. Please provide the original text to be translated.



Disclaimer

This article is provided solely for professional research, industry discussion, and informational purposes. Any references to brands, companies, products, technologies, or policies are made for factual reporting and analytical purposes only, and do not constitute endorsement, recommendation, promotion, or advertising by 2Firsts.

Nicotine-containing products, including but not limited to cigarettes, e-cigarettes, heated tobacco products, and nicotine pouches, carry significant health risks. Readers are responsible for complying with all applicable laws and regulations in their respective jurisdictions, including age restrictions and access limitations.

The information contained in this article should not be regarded as investment, legal, medical, regulatory, or commercial advice. While 2Firsts strives to ensure the accuracy and reliability of its content, it does not assume liability for any direct or indirect loss arising from errors, omissions, inaccuracies, or reliance on the information contained herein.

This article is not intended for individuals below the legal age for accessing tobacco or nicotine-related information in their jurisdiction.

 

Copyright Notice

This article is either original content produced by 2Firsts or content reproduced, translated, summarized, or adapted from third-party sources with attribution where applicable. The intellectual property rights of the original content remain with 2Firsts or the respective original rights holders.

No individual or organization may copy, reproduce, distribute, republish, modify, translate, or otherwise use this content without prior authorization. Any unauthorized use may result in legal action.

For copyright-related inquiries, corrections, or removal requests, please contact: info@2firsts.com.

 

AI-Assisted Translation and Editing Notice

Portions of this article may have been translated, edited, or reviewed with the assistance of artificial intelligence tools to improve efficiency and readability. Due to the limitations of AI-assisted translation and editing, discrepancies, omissions, or inaccuracies may exist when compared with the original source.

Where applicable, readers are advised to refer to the original source for the most complete and accurate information. If you identify any errors or believe that any content infringes upon your rights, please contact us at info@2firsts.com, and we will review and address the matter promptly.

Australia’s Daily Smoking Rate Falls to Record Low of 5.8% as Nicotine Use Patterns Shift
Australia’s Daily Smoking Rate Falls to Record Low of 5.8% as Nicotine Use Patterns Shift
According to the Australian Institute of Health and Welfare’s National Drug Strategy Household Survey, daily smoking among Australians aged 18 and over fell to a record low of 5.8% in 2025. Health Minister Mark Butler said Australia now has around 500,000 fewer daily smokers than three years ago and credited the government’s vaping reforms as part of broader progress. Among people aged 14 and over, daily smoking declined from 8.3% in 2022-23 to 5.6% in 2025. Daily vaping rates stabilised at 3.6%, while the government also moved to further restrict access to nicotine pouches through unapproved therapeutic import pathways.
Jul.21
InterTabac 2026: Further Sessions on Regulation, Market Access and Innovation Confirmed; 2FIRSTS to Host China Market Forum
InterTabac 2026: Further Sessions on Regulation, Market Access and Innovation Confirmed; 2FIRSTS to Host China Market Forum
InterTabac 2026 will bring together international experts to discuss European regulation, tax policy, Track & Trace, market access, retail impacts, consumer behavior and innovation. Sessions will also examine Poland’s tobacco-growing perspective and the growing fragmentation of Europe’s tobacco and nicotine market. Media partner 2FIRSTS will host the second “2FIRSTS Connect at InterTabac” on September 16, focusing on developments in China’s tobacco and nicotine industry.
Aug.06
2Firsts Hosts U.S. Market Mid-Year Briefing: Companies Need to Reassess Product and Market-Access Strategies
2Firsts Hosts U.S. Market Mid-Year Briefing: Companies Need to Reassess Product and Market-Access Strategies
2Firsts held its 2026 U.S. Market Compliance and Development Mid-Year Briefing in Shenzhen, China, on July 28. The discussion examined how state-level requirements, proposed foreign-establishment registration rules and expanding supply-chain responsibilities are changing product and investment decisions in the U.S. tobacco and nicotine market.
Jul.29
PMI Global Communications Chief Moira Gilchrist: Why AI Matters More Than Ever in the Smoke-Free Transition
PMI Global Communications Chief Moira Gilchrist: Why AI Matters More Than Ever in the Smoke-Free Transition
Philip Morris International (PMI) Chief Global Communications Officer Moira Gilchrist said artificial intelligence is changing how companies understand audiences, manage owned information channels and communicate business transformation. PMI is using AI-generated audience personas to test messaging while optimizing its corporate website and other owned channels for large language models. As PMI continues its transition from cigarettes toward smoke-free products, Gilchrist said owned data and corporate channels are becoming increasingly important in demonstrating the scale of that transformation.
Aug.26
UK PM Andy Burnham Reshapes Vape Retail Rules as Licensing Could Raise Barriers for New Shops
UK PM Andy Burnham Reshapes Vape Retail Rules as Licensing Could Raise Barriers for New Shops
UK Prime Minister Andy Burnham is pushing a high street reform agenda that could give local authorities greater powers over commercial activity, including vape retail. The reforms could involve expanded planning powers and a potential vape retail licensing system, allowing councils to play a larger role in store locations and market access. The measures are part of the UK’s broader shift toward tighter vape regulation, although no nationwide vape retail restrictions have yet been implemented.
Aug.11
Product | IQOS ILUMA i REMIX Limited Edition Launches in Japan, Bringing New Design Elements to Heated Tobacco Devices
Product | IQOS ILUMA i REMIX Limited Edition Launches in Japan, Bringing New Design Elements to Heated Tobacco Devices
Philip Morris Japan (PM Japan) has introduced the IQOS ILUMA i REMIX Limited Edition series, including the IQOS ILUMA i Prime REMIX, IQOS ILUMA i REMIX and IQOS ILUMA i ONE REMIX devices. The limited-edition models were officially announced in Japan on June 9, 2026, and began a phased market rollout from June 10. Featuring gradient color designs and visual customization elements, the collection highlights PMI’s continued use of limited editions to enhance brand experience within its heated tobacco portfolio.
Innovation
Jul.21 by 2Firsts Perspectives