A study titled "Effects of Mango and Mint Pod-based E-cigarette Aerosol Inhalation on Inflammatory Status of the Mouse Brain, Lung, Heart, and Colon" published in eLife has found that Juul aerosol exposure affects different organs of mice and analyses how specific e-cigarette flavors contribute to this effect.
In this research study, a team led by Dr. Laura Crotty Alexander, a medical professor and director of the ICU in the UC San Diego Health System and the VA San Diego Healthcare System, investigated the effects of aerosols produced by flavored electronic cigarettes (JUUL) on inflammatory biomarkers in the brain, lungs, heart, and colon. Participants in the study inhaled the aerosol three times a day for three months.
Crotty and her team also studied the effects of the most popular flavors of the brand: mint and mango. The researchers discovered several elevated inflammation markers, with the most significant being in the brain. They also found changes in gene expression within brain regions related to motivation and reward processing.
Analysis of colon samples showed an increase in the expression of inflammatory genes, which is associated with an increased risk of gastrointestinal diseases. Meanwhile, the inflammation levels in heart tissue seem to have lowered, leading the authors to suggest that this could indicate a suppression of the immune system.
E-cigarettes and heart health.
Researchers from Ohio State University's medical school recently published a study in the American Heart Association (AHA) journal, titled "E-cigarette aerosol impairs left ventricular function in adolescent mice.
According to a study, mice exposed to a mixture of electronic cigarette aerosols containing propylene glycol, vegetable glycerin, and nicotine from the equivalent of around 12 years old in humans until around 30 years old, experienced a decline in heart function in males over time. However, interestingly, there was no adverse effect observed in the heart function of female mice.
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