2Firsts Convenes 2025 Insight Forum on Dual Challenges of U.S. NGP Regulation & Tariff Trends/ Closed-Door Forum on Nicotine Pouch PMTA Technical Analysis

May.16
2Firsts Convenes 2025 Insight Forum on Dual Challenges of U.S. NGP Regulation & Tariff Trends/ Closed-Door Forum on Nicotine Pouch PMTA Technical Analysis
2Firsts hosted a seminar in Shenzhen on 2025 Insight Forum on Dual Challenges of U.S. NGP Regulation & Tariff Trends/ Closed-Door Forum on Nicotine Pouch PMTA Technical Analysis. Experts from CSUR provided in-depth analysis of compliance pathways, aiming to help the industry navigate dual challenges of regulation and tariffs.

【2Firsts-Shenzhen】On the afternoon of April 16, the leading global aerosol technology media and think tank 2Firsts successfully held a closed-door seminar in Shenzhen Qianhai, titled "2025 Insight Forum on Dual Challenges of U.S. NGP Regulation & Tariff Trends/ Closed-Door Forum on Nicotine Pouch PMTA Technical Analysis".

 

The forum was divided into two sessions, with the first session focusing on the technical analysis of nicotine pouches' PMTA, delving into the compliance pathway of nicotine pouches in the US market. The second session revolved around the interpretation of the trends of new tobacco regulations and dual tariff challenges in the United States in 2025, providing attendees with insights into the future regulatory and tariff policies of the US. The conference attracted representatives of dozens of nicotine pouch and e-cigarette companies in terms of technology and compliance, collectively discussing key industry development issues and providing valuable insights and strategies for addressing future challenges.

 

Dr. Andrea Patton, the head of epidemiological research at the Centre for Substance Use Research (CSUR), along with co-director Gabriel Barnard, were invited to attend this seminar and each gave a keynote speech.

 

Dr. Andrea Patton gave a speech titled "Use of Zyn Nicotine Pouches in the United States: Quantifying Population-Level Risk and Benefit in a PMTA Framework.

 

美国CSUR受邀参加2FIRSTS尼古丁袋PMTA技术分析暨美国监管动向研讨会并发表主题演讲
Dr. Andrea Patton delivering a video speech | Image source: 2Firsts

 

Using ZYN's PMTA (Premarket Tobacco Product Application) approval as a case study, she systematically introduced the public health standards that new tobacco products need to meet in order to be approved for market in the United States. She analyzed the key types of research involved in the PMTA framework, and detailed how to scientifically quantify the risks and benefits at the population and non-population levels.

 

Dr. Patton pointed out that the approval of ZYN provides a "reference benchmark" for future applicants to evaluate the "level of acceptable use" of products among different populations, demonstrating significant industry implications.

 

Gabriel Barnard gave a keynote speech titled "A Perception and Behavioral Strategy to Quantify the Public Health Impact of an Oral Nicotine Pouch Product in the United States".

 

2Firsts Convenes 2025 Insight Forum on Dual Challenges of U.S. NGP Regulation & Tariff Trends/ Closed-Door Forum on Nicotine Pouch PMTA Technical Analysis
Video footage of Gabriel Barnard's speech on stage | Image source: 2Firsts

 

During the speech, Gabriel Barnard provided a detailed analysis of the Pre-Market Tobacco Product Application (PMTA) review framework, outlining the specific types of research and key information requirements that nicotine pouch manufacturers need to focus on during the application process. He presented three recommended research directions to help applicants meet the public health assessment standards of PMTA.

 

·Actual Use Study

·Behavior Intent ions and Risk Perceptions Study

·Label Comprehension and Usability Study

 

Subsequently, Gabriel Barnard systematically explained the important role of these three types of research in PMTA applications from the dimensions of regulatory compliance and scientific basis, providing practical strategic guidance for the registration path of nicotine pouch products.

 

Dr. Andrea Patton and Gabriel Barnard's professional presentations were widely praised and enthusiastically received by attendees. Many delegates expressed that the insights and compliance guidance shared by the two experts provided them with valuable industry knowledge, helping them to gain a deeper understanding of key assessment criteria for PMTA applications, methods for quantifying product benefits and risks, and the application of multidisciplinary research in compliance processes.

 

At the same time, attendees also expressed sincere gratitude to the two organizers, believing that this forum has built a high-quality compliance communication platform, greatly promoting communication and collaboration among various industry participants, and playing a positive role in pushing the new tobacco industry to take solid steps on the path of compliant development.

 

We welcome news tips, article submissions, interview requests, or comments on this piece.

Please contact us at info@2firsts.com, or reach out to Alan Zhao, CEO of 2Firsts, on LinkedIn


Notice

1.  This article is intended solely for professional research purposes related to industry, technology, and policy. Any references to brands or products are made purely for objective description and do not constitute any form of endorsement, recommendation, or promotion by 2Firsts.

2.  The use of nicotine-containing products — including, but not limited to, cigarettes, e-cigarettes, nicotine pouchand heated tobacco products — carries significant health risks. Users are responsible for complying with all applicable laws and regulations in their respective jurisdictions.

3.  This article is not intended to serve as the basis for any investment decisions or financial advice. 2Firsts assumes no direct or indirect liability for any inaccuracies or errors in the content.

4.  Access to this article is strictly prohibited for individuals below the legal age in their jurisdiction.

 

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AI Assistance Disclaimer

 

This article may have been enhanced using AI tools to improve translation and editorial efficiency. However, due to technical limitations, inaccuracies may occur. Readers are encouraged to refer to the cited sources for the most accurate information.

We welcome any corrections or feedback. Please contact us at: info@2firsts.com

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