Nicotine Exposure in Pregnancy Affects Adult Sleep Patterns

This study, titled "Early Nicotine or Diazepam Exposure Induces Long-Term Sleep Changes and Hippocampal Corticosteroid Receptor Downregulation in Adult Mice," was published in a scientific journal with the goal of determining the effects of nicotine and its byproducts on adults who were exposed during the perinatal period.

A research team exposed pregnant mice to passive smoking levels of nicotine and discovered that as adults, these mice had a significant reduction in sleep between resting and active phases.

According to Professor Giovanna Zoccoli, a researcher from the Department of Biomedical and Neuromotor Sciences at the University of Bologna, "The findings of this study suggest that adult sleep may be influenced by events that occurred in early life". "Based on our data, controlling environmental factors during pregnancy is crucial not only for women's health but also for the health of their offspring.

The study also found that this prenatal smoking exposure altered the expression and balance of hippocampal cortical hormone receptors. Zuccolini also added, "Our data suggests that sleep changes and downregulation of hippocampal cortical hormones occur simultaneously." "These results indicate that nicotine intake during pregnancy is a stress factor that affects the hippocampus development of offspring and their adult sleep patterns.

Do electronic cigarettes have an adverse effect on the heart?

A recent study exposed the heart cells of mice to vapor in a petri dish, concluding that vaping is harmful to the heart. Award-winning science writer, bestselling author, and chairman of the American Council on Science and Health, Hank Campbell explains why these findings are flawed.

A research report titled "In Vitro and In Vivo Cardiac Toxicity of Flavoring Nicotine E-Cigarettes" states that mice who inhaled vanillin had increased sympathetic nervous system dominance in heart rate variability measurements. Campbell stated, "A new paper claims that vaping, not smoking, puts the heart at risk, but their research does not support this claim. Instead, they mixed chemicals with heart cells in a petri dish and conducted experiments on mice. Both experiments are good exploratory studies, but scientifically, they cannot support the authors' conclusions stated in their press release.

According to Campbell, 'Mice aren't humans. If the FDA only studied them or cells grown in petri dishes, no drugs would ever make it to the approval process.' Furthermore, he explained that in this study, HL-1 cells from mice and later human cells produced in the lab were inundated with a large amount of chemicals from e-cigarettes that the human body wouldn't come into contact with for another 40,000 years.

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