Roberto Sussman and Sebastien Soulet's Study on E-Cigarettes' Metal Content

Sep.19.2022
Roberto Sussman and Sebastien Soulet's Study on E-Cigarettes' Metal Content
Roberto Sussman and Sebastien Soulet offer a detailed assessment of the metal content in electronic cigarettes in a special edition of Toxicology journal.

Roberto Sussman and Sebastien Soulet have published a comprehensive review of 12 laboratory studies examining the metal content of e-cigarette emissions. The paper, titled "Pros and Cons of Electronic Cigarettes", appears in a special edition of the journal "Toxins".


Professor Andrzej Sobczak and Dr. Leon Kośmider wrote in the preface of a special edition that "electronic cigarettes (EC) have been present on the consumer market for over a decade, with the number of scientific publications in the PubMed database now exceeding 7,000.


Despite the large number of publications, the scientific community has not yet reached a consensus on their safety. However, it should be emphasized that comparing the amount of tobacco smoke and aerosol produced by e-cigarettes shows that the toxic compound content in aerosols is much lower than in tobacco smoke. This can be seen as a way to reduce health damage to smokers who cannot or do not want to quit using traditional methods.


They added that randomized controlled studies have shown that electronic cigarettes help with smoking cessation. The special issue covers:


Research on the chemical composition of e-cigarette liquids and vapors focuses on the impact of electronic cigarettes, snuff, and high-temperature non-combustible tobacco products on health. Studies have been conducted on the e-cigarette population, intervention research targeting youth, and smoking cessation research for adult smokers. Dr. Soulet and Dr. Sussman contributed to a paper analyzing 12 laboratory studies on the metal content of e-cigarette emissions.


Sebastien Soulet works for Ingesciences in France and Roberto Sussman works at the National Autonomous University of Mexico's Institute of Nuclear Sciences.


They wrote: "There is a legitimate concern for potential harm to users caused by the inhalation of metal compounds emitted from e-cigarette aerosol. We conducted a rigorous review of laboratory studies published after 2017 regarding the metal content in EC aerosol, with a focus on the consistency between experimental design, real-life device usage, and appropriate evaluation of exposure risk.


All experiments reporting levels of toxicological parameters for certain metals (such as nickel, lead, copper, and manganese) show the following experimental deficiencies:


The high-powered sub-ohm tank equipment, tested through an inhalation agreement, has meticulously designed airflow and suction capabilities suitable for low-powered devices. This testing inevitably involves overheating conditions conducive to the production of toxic substances and aerosols that may have a repellent effect on human users. Experimental results have shown that exposure levels were miscalculated months and years prior to the experiment, and thus corrosion effects cannot be ruled out. Critical information regarding the characteristics of the inhalation chamber and storage tank equipment, experimental methods and results, has not been disclosed, hindering the possibility of interpreting and replicating the results. Generally speaking, the metal exposure levels produced by low-powered devices that do not exhibit these deficiencies are much lower than strict toxicological reference markers.


We believe that this review provides useful guidance for a more objective assessment of the risks associated with EC aerosol emissions, and indicates the need to upgrade current laboratory testing standards.


Statement:


This article is compiled from third-party information and is intended for industry communication and learning purposes only.


This article does not represent the views of 2FIRSTS, and 2FIRSTS cannot confirm the truthfulness or accuracy of the content. The compilation of this article is solely for industry exchange and research.


Due to limitations in the ability to translate accurately, the translated article may not express the exact same meaning as the original. Therefore, it is advised to refer to the original article for accuracy.


2FIRSTS maintains full alignment with the Chinese government on all domestic, Hong Kong, Macau, Taiwan, and foreign-related expressions and positions.


The copyright of the compiled information belongs to the original media and author. If there is a violation, please contact us to remove it.


This document has been generated through artificial intelligence translation and is provided solely for the purposes of industry discourse and learning. Please note that the intellectual property rights of the content belong to the original media source or author. Owing to certain limitations in the translation process, there may be discrepancies between the translated text and the original content. We recommend referring to the original source for complete accuracy. In case of any inaccuracies, we invite you to reach out to us with corrections. If you believe any content has infringed upon your rights, please contact us immediately for its removal.

South Korea Postal Service Launches Heated Tobacco Device Recycling Program Through Nationwide Post Offices and Mailboxes
South Korea Postal Service Launches Heated Tobacco Device Recycling Program Through Nationwide Post Offices and Mailboxes
Korean postal system launches nationwide heated tobacco device recycling through post offices and mailboxes, aiming to increase recycling rates.
Feb.10 by 2FIRSTS.ai
SICPA Secures Five-Year UK Vape Tax Stamp Contract
SICPA Secures Five-Year UK Vape Tax Stamp Contract
HM Revenue and Customs (HMRC) has awarded a five-year contract to Swiss technology company SICPA and Cartor Security Printers to implement the United Kingdom’s new vaping duty stamp and track-and-trace system, beginning in April 2026.
Market
Feb.24
India Tobacco Board urges Finance Minister Nirmala Sitharaman to revisit cigarette duty hike
India Tobacco Board urges Finance Minister Nirmala Sitharaman to revisit cigarette duty hike
The Tobacco Board, under the administrative control of India’s Department of Commerce, has written to Finance Minister Nirmala Sitharaman (Nirmala Sitharaman) flagging the adverse impact of an “unprecedented” increase in cigarette excise duties on the industry and on millions of farmers and workers, and urging a revision of duty rates.
Feb.11 by 2FIRSTS.ai
FDA Outlines Manufacturing Requirements as Critical to ENDS PMTA Success
FDA Outlines Manufacturing Requirements as Critical to ENDS PMTA Success
FDA officials said manufacturing consistency is a core prerequisite for ENDS PMTA reviews, not a procedural formality. During its February 10, 2026 roundtable, the agency outlined expectations for quality management systems, manufacturing documentation, nicotine control, stability studies, and risk mitigation, emphasizing that robust manufacturing evidence underpins determinations of whether products are appropriate for the protection of public health.
Feb.11
Imperial Brands to Close Langenhagen Cigarette Factory by 2027
Imperial Brands to Close Langenhagen Cigarette Factory by 2027
Imperial Brands said it will gradually close the Reemtsma factory in Langenhagen near Hanover by 2027 after efforts to find a buyer failed to produce a sustainable agreement. The factory has produced cigarettes since 1971 and currently affects around 600 employees. The company said it had examined all realistic options over recent months but did not receive a binding offer from a potential buyer.
Mar.27 by 2FIRSTS.ai
Philip Morris Korea to Launch IQOS Iluma i One “Electric Purple” Color, Expanding Into Major Convenience Store Channels From May
Philip Morris Korea to Launch IQOS Iluma i One “Electric Purple” Color, Expanding Into Major Convenience Store Channels From May
Philip Morris Korea said on March 31 that it will begin selling the new “Electric Purple” color for the heated tobacco device IQOS Iluma i One at major convenience stores nationwide in South Korea starting May 2. The color will first be introduced on April 10 at the official IQOS online store and nine IQOS directly operated stores nationwide. To mark the expansion of its sales channels, the company will run promotions at major convenience stores through May 20.
Mar.31