Stanford Study Shows Americans Inhaling Unintended Substances

Jun.02.2022
Stanford Study Shows Americans Inhaling Unintended Substances
A new study from Stanford University reveals that Americans are vaping non-nicotine substances, which can harm the lungs.

According to a report by FUTURITY website, a new study conducted by Stanford University reveals that Americans are consuming substances they never thought of inhaling before, including melatonin, essential oils, tea, vitamins, caffeine, and other non-nicotine substances.

 

This survey questioned the usage habits of over 6,000 adolescents, young adults, and adults aged 13-40. It is the first nationwide sample survey on the intake of non-nicotine products.

 

Scientists say that while some non-nicotine substances may be safe for ingestion, inhaling them through vaporization may harm the lungs. Chemicals, solvents, and flavors found in non-nicotine vaping products also exist in nicotine vaping products and have been shown to have harmful effects unrelated to nicotine.

 

According to Bonnie Halpern-Felsher, a professor of pediatrics at Stanford University School of Medicine and a senior author of a paper on the online edition of the Journal of the American Medical Association, "Our most striking finding was that nearly 14% of youths and 24% of young adults had used non-nicotine electronic cigarettes.

 

Non-nicotine electronic cigarettes currently evade regulation by the Food and Drug Administration for nicotine e-cigarettes or intake supplements, which means there are no restrictions on the equipment, ingredients, or marketing of these products. Additionally, there is no age limit for purchasing these products. According to Halpern-Felsher, many sellers make unfounded health claims, making electronic cigarettes appear safe to both youth and adults, despite their safety never being tested.

 

According to Halpern-Felsher, "Anything that is purchased, heated, and inhaled without a prescription is harmful to your lungs.

 

Investigation reveals

 

Researchers surveyed teenagers, young adults, and adults living across the United States, focusing on four age groups: 13-17, 18-20, 21-24, and 25-40. These groups represent different stages of development: early adolescence, young adulthood below the legal age for nicotine e-cigarette sales, prefrontal brain maturation during young adulthood, and adulthood. Participants' gender, race, and ethnicity were representative of the US population.

 

Participants answered questions about their use of non-nicotine electronic cigarettes, nicotine-containing electronic cigarettes, and combustible cigarettes. The survey asked if participants had ever used these products, if they had used them recently, and the timing of their first use of each product. The survey also included questions about usage patterns, specific brands, preferred flavors, and ingredients used in non-nicotine vaping devices.

 

Overall, approximately 26% of participants reported trying non-nicotine e-cigarettes, with nearly 17% reporting use within the past 30 days and approximately 12% within the past 7 days. Usage varied according to age, with the 21-24 year old group reporting the highest proportion of non-nicotine use (approximately 38%), followed by the 25-40 year old group at nearly 33%.

 

Approximately 14% of 13 to 17-year-olds and 24% of 18 to 20-year-olds have reported trying non-nicotine electronic cigarettes, with more than half of those individuals using these devices multiple times. On average, participants reported trying non-nicotine e-cigarettes at a younger age than nicotine e-cigarettes, raising concerns that non-nicotine devices could be a pathway to using nicotine-containing products.

 

What substances are people inhaling?

 

Many young survey participants are unaware of what they are vaping. Approximately 24% of teenagers aged 13 to 17 and 19% of young adults aged 18 to 20 reported that they do not know what is in the non-nicotine e-cigarettes they use.

 

Popular substances for consumption among teenagers and young people include tetrahydrocannabinol (THC), an active compound found in marijuana. Other substances include melatonin, cannabidiol (CBD), a non-psychoactive derivative of marijuana, essential oils, caffeine, and tea.

 

Among adults aged 25-40, caffeine, vitamin B, tea, and tetrahydrocannabinol are all popular. A complete list of substances found in non-nicotine electronic cigarettes includes vitamin C, lavender, essential oils, propylene glycol, glycerin, and other flavorings.

 

Halpern-Felsher stated that while the use of marijuana compounds isn't surprising, the popularity of other substances is unexpected and concerning.

 

The Food and Drug Administration has designated certain chemicals added to food, including vitamins and some flavorings, as "generally recognized as safe." However, this is not always the case.

 

According to Halpern-Felsher, the designation of GRAS (an indicator used by the US FDA to evaluate safety of food additives) means that certain things are safe to consume or use as a skin cream. However, there is a significant difference when it comes to inhaling aerosols produced by heating substances. This is where it affects your lungs.

 

Halpern-Felsher emphasized that the safety and potential risks or side effects of inhaling these substances are still not clear. Furthermore, non-nicotine e-cigarettes share common ingredients with nicotine-containing e-cigarettes, such as propylene glycol, glycerin, and flavoring compounds, all of which are known to be harmful to the lungs.

 

Unknown dangers

 

Halpern-Felsher has stated that for several common substances that are smoked, our existing knowledge of their chemical properties indicates that they pose harm to the lungs, and consumers should remain cautious.

 

She said, 'We really need toxicologists and other scientists to help us understand the impact of these chemicals on our bodies and by what mechanisms.' For example, she noted that excessive amounts of vitamins can have toxic effects. Pulmonary surfactants are oily substances produced by the body to lubricate lung air sacs. Inhaling evaporated fatty substances, such as essential oils, glycerin (a common ingredient in all e-cigarettes), and aromatic compounds, may interfere with lung function.

 

The message for everyone, especially young people, is that any inhaled aerosol, except for medication prescribed by a doctor (such as asthma treatment), could potentially be dangerous.

 

Halpern-Felsher stated, "Maintaining the health of our lungs has never been as critical as it is now during the COVID-19 pandemic.

 

She hopes that these findings will stimulate policy changes to better regulate the electronic cigarette industry, especially in terms of protecting youth.

 

We cannot allow non-nicotine products to be available for purchase in the open market anymore, especially considering the fact that young people are sharing and inhaling them without knowing what substances they contain. We need regulation and labelling measures to ensure that these products do not end up in the hands of young people.

 

Source: FUTURITY.

 

This document has been generated through artificial intelligence translation and is provided solely for the purposes of industry discourse and learning. Please note that the intellectual property rights of the content belong to the original media source or author. Owing to certain limitations in the translation process, there may be discrepancies between the translated text and the original content. We recommend referring to the original source for complete accuracy. In case of any inaccuracies, we invite you to reach out to us with corrections. If you believe any content has infringed upon your rights, please contact us immediately for its removal.

Singapore hikes vape penalties: users face up to S$10,000; importers up to 9 years
Singapore hikes vape penalties: users face up to S$10,000; importers up to 9 years
Singapore Parliament passes law to significantly increase penalties for e-cigarette possession, use, import, and sale, effective May 1.
Mar.09 by 2FIRSTS.ai
Smoore, Distributors Move to Toss Cannabis Vape Price-Fixing Suit
Smoore, Distributors Move to Toss Cannabis Vape Price-Fixing Suit
Several vape manufacturers and distributors, including Shenzhen Smoore Technology Co. Ltd., Smoore International Holdings, 3Win Corp., Jupiter Research LLC, Canna Brand Solutions, and Greenlane Holdings Inc., have filed motions seeking dismissal of consumer claims in consolidated antitrust litigation in the U.S. District Court for the Northern District of California.
Events
Feb.24
Japan Tobacco Launches Nordic Spirit Nicotine Pouches in Japan; Nationwide Rollout Starts April 6
Japan Tobacco Launches Nordic Spirit Nicotine Pouches in Japan; Nationwide Rollout Starts April 6
Japan Tobacco (JT) has introduced the new Nordic Spirit nicotine pouch brand in Japan. The Cola Fizz Medium flavor began early sales on March 3, 2026 via the CLUB JT online shop, and will be rolled out sequentially from April 6 through nationwide channels including 7-Eleven, Lawson, and NewDays. The Berry Mix Medium flavor is expected to launch on CLUB JT around mid-March.
Mar.04 by 2FIRSTS.ai
Study: Links between internalizing mental health symptoms and nicotine/tobacco use vary by gender identity among U.S. adolescents
Study: Links between internalizing mental health symptoms and nicotine/tobacco use vary by gender identity among U.S. adolescents
A study using 2020–2023 U.S. data from the ITC Youth Tobacco and Vaping Survey (ages 16–19) reports that both nicotine/tobacco use and internalizing mental health (IMH) symptoms vary across disaggregated gender identities, and that gender identity moderates the relationship between IMH symptoms and product use.
Feb.27 by 2FIRSTS.ai
The UK government plans to expand the scope of its e-cigarette ban to include playgrounds, off-campus areas, and areas outside hospitals.
The UK government plans to expand the scope of its e-cigarette ban to include playgrounds, off-campus areas, and areas outside hospitals.
Government plans would ban vaping in cars carrying children and restrict smoking, vaping and heated tobacco in settings including playgrounds and outside schools across England, subject to a 12-week public consultation. The proposals also say indoor spaces where smoking is already banned would become vape- and heated-tobacco-free, and areas outside hospitals would be included.
Feb.13 by 2FIRSTS.ai
Elfbar warns flavour bans could push over 50,000 Scottish vapers back to smoking
Elfbar warns flavour bans could push over 50,000 Scottish vapers back to smoking
Elfbar said restricting vape flavour choices—potentially under the Tobacco and Vapes Bill—could disrupt established quitting behaviours and increase relapse risk among former smokers. An Opinium survey commissioned by the company reported fruit and sweet flavours have risen in popularity among adult vapers quitting smoking in Scotland, with 62% now using them most often to quit, up from 34% in December 2024.
Feb.28 by 2FIRSTS.ai